In a cohort of 2138 oral cancer patients from Singapore and India, Singh M. et al. demonstrated that young adults had a pathologically more aggressive form of oral cancer, although 5-year overall and disease specific survival did not differ between younger and older patients due to more intensive therapy. Nevertheless, the loss of life from early-onset disease has a greater socio-economic impact than in the elderly, from a major loss in economic productivity and societal involvement.
